3-pyr-Cytisine snic acid Smiles: OC(CNCCC1=CNC2=CC=CC=C12)CN1C2=CC=CC=C2C2=CC=CC=C12

Smiles: OC(CNCCC1=CNC2=CC=CC=C12)CN1C2=CC=CC=C2C2=CC=CC=C12

CRBN-PROTAC-14a

Smiles: C[C@]12CC[C@@H](O)[C@@](C)(CO)[C@@H]1CC[C@H]1C[C@@H]3C[C@]21CC[C@]3(O)CO

24 hours) stimulates MUC5AC expression and mucin Secretion in HT29-MTX Cells (human)

(IC50 values are 0

3-pyr-Cytisine snic acid Smiles: OC(CNCCC1=CNC2=CC=CC=C12)CN1C2=CC=CC=C2C2=CC=CC=C123 pyr Cytisine is a partial agonist of 42 receptor with Ki values of 0. 91, 119 and 1100 nM for 42, 34 and 7 receptors, respectively . The alpha 4 beta 2 nicotinic receptor (42 receptor) is a nicotinic acetylcholine receptor participated in learning and is widely expressed in the central nervous system. Also, 42 receptor has the highest affinity for nicotine. 3 pyr Cytisine is an 42 receptor partial agonist. In cells expressed 42 receptor, 3 pyr Cyt