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NE 52-QQ57 (Compound 13) shows a significant anti-inflammatory effect in the rat antigen induced arthritis model after oral administration at 30 mg/kg bid for 20 days[1]
InChi: InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3
212-2 mesylate
InChiKey: VMZMNAABQBOLAK-DBILLSOUSA-N
inhibits autophosphorylation of BTK on Tyr223 in cells with an EC50 of 475 nM and inhibits phosphorylation of a downstream effector PLCγ2 (Tyr759) with an EC50 of 318 nM
N-acetyl Dapsone D4 003ompound Library of Histone Demethylase NE 52-QQ57 (Compound 13) showsN acetyl Dapsone D4 (MADDS D4) is the deuterium labeled N acetyl Dapsone, which is a metabolite of Dapsone. Product information CAS Number: 2070015 08 4 Molecular Weight: 294. 36 Formula: C14H14N2O3S Synonym: MADDS D4 Chemical Name: N {4 [4 amino(2, 3, 5, 6 H)benzenesulfonyl]phenyl}acetamide Smiles: [2H]C1=C(N)C([2H])=C([2H])C(=C1[2H])S(=O)(=O)C1C=CC(=CC=1)NC(C)=O InChiKey: WDOCBIHNYYQINH USSMZTJJSA N InChi: InChI=1S C14H14N2O3S c1 10(17)16 12 4 8
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