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an active component isolated from Astragalus membranaceus
Formula: C11H11NO2
On isolated rat ileum intestine
Smiles: C[C@]12C[C@@H](O)[C@@H]3C[C@@]1(O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)[C@]3(COC(=O)C1C=CC=CC=1)C(=O)O2
0 μg/mL effectively blocks fatty acid synthesis and induces cell death in a dose-dependent manner
trans-AUCB opurvalanol A an active component isolated fromIC50: 0. 5 nM trans AUCB is a potent inhibitor of soluble epoxide hydrolase (sEH). Soluble epoxide hydrolase (sEH) can convert epoxides to their corresponding diols. Inhibitors of sEH have anti hypertensive, anti inflammatory, neuroprotective, and cardioprotective effects. In vitro: A previous study showed that the pretreatment with DAPT could substantially potentiate the growth inhibition caused by t AUCB in U251 and U87 cells. Moreover, the
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