ARP 101 Catalog No.:M23013-C Smiles: CN([C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N1CCCCO1)OC)[C@@H](C)CC)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C

Smiles: CN([C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N1CCCCO1)OC)[C@@H](C)CC)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C

BV2 murine microglial cells) exhibits anti-inflammatory properties by suppressing the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase signaling pathways in LPS-stimulated BV2 microglial cells

inhibition of the overall reaction was found to be competitive with the allosteric activator of this enzyme

Saikogenin A

Difloxacin is extensively metabolized by glucuronidation and secreted into bile

ARP 101 Catalog No.:M23013-C Smiles: CN([C@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](CC1=CNC2=CC=CC=C12)C(=O)N1CCCCO1)OC)[C@@H](C)CC)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)CARP 101 is a selective MMP 2 inhibitor with IC50 value of 0. 81nM. MMP 2 is an enzyme and involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction and tissue remodeling, as well as in disease processes, such as arthritis and metastasis . ARP 101 shows inhibition of fibrosarcoma HT1080 cell growth in vitro. ARP 101 has shown ~250 fold selectivity of MMP 2 over MMP 1 and ~100 fold