5-Aminolevulinic acid Hydrochloride - CAS# 5451-09-2 respladib) SR9011 was used at 5-10

SR9011 was used at 5-10 µM concentration in vitro and in cellular assays

a receptor tyrosine kinase mutated in many tumor cell types

Edupuganti R

Discovery of NVP-LDE225

In ovariectomized (OVX) mouse model

5-Aminolevulinic acid Hydrochloride - CAS# 5451-09-2 respladib) SR9011 was used at 5-10Aminolevulinic acid, also known as ALA, is a topically administered metabolic precursor of protoporphyrin IX. After topical administration, aminolevulinic acid (ALA) is converted to protoporphyrin IX (PpIX) which is a photosensitizer. When the proper wavelength of light activates protoporphyrin IX, singlet oxygen is produced, resulting in a local cytotoxic effect. In 1999, FDA approved this drug for for actinic keratosis. Product information CAS