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Shows selectivity for PAR2 over PAR1
nicotine addiction
(2015) Nat Chem Biol
Smiles: COC(=O)[C@H](CC1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NCCC(C)(C)C
PF-4136309 is potent in inhibiting CCR2 mediated signaling events such as intracellular calcium mobilization and ERK (extracellular signal-regulated kinase) phosphorylation with IC50 values of 3
Chitinase-IN-1 one Shows selectivity for PAR2 overChitinase IN 1 is a insect chitinase and N acetyl hexosaminidase inhibitor and pesticide; 50 uM 20 uM compound concentration's inhibitory percentage are 75% 67% for chitinase N acetyl hexosaminidase respectively. Product information CAS Number: 1579991 61 9 Molecular Weight: 352. 41 Formula: C18H16N4O2S Chemical Name: 3 (2 {[(5 methyl 1,3,4 thiadiazol 2 yl)methyl]amino}ethyl) 3 azatricyclo[7. 3. 1. 0,]trideca 1(12),5,7,9(13),10 pentaene 2,4 dione
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