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which demonstrates both potential opportunity and possible challenges to therapeutic agonism
31)32)18-38-11-9-37(2)10-12-38
García-Fernández LF
12-hexaene dihydrochloride
69)70)73-61(84)49-23-14-22-48(40-49)53-27-28-54-64(74-53)91-66(75-54)76-56(82)43-90-39-38-89-37-36-88-35-29-72-63(86)59(57(45-16-8-5-9-17-45)46-18-10-6-11-19-46)78-62(85)55-24-15-30-81(55)65(87)58(47-20-12-7-13-21-47)77-60(83)44(2)71-3/h5-6
PG106 yl-α-phenylnitrone which demonstrates both potential opportunityPG106 is a potent and selective human melanocortin 3 (hMC3) receptor antagonist (IC50=210 nM) and has noactivity at hMC4 receptors (EC50=9900 nM) and hMC5 receptor. Product information CAS Number: 944111 22 2 Molecular Weight: 1008. 18 Formula: C51H69N13O9 Chemical Name: (3S,6S,9R,16S,24S) 6 (3 carbamimidamidopropyl) 2,5,8,11,15,18 hexahydroxy 16 [(Z) {1 hydroxy 2 [(Z) (1 hydroxyethylidene)amino]hexylidene}amino] 3 [(1H indol 3 yl)methyl] 9