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Vinblastine sulfate Size:Solid 2 mg CS-0087356

SKU: 3446795053

4.2
USD80.00 USD117.00

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Description

CS-0087356

InChi: InChI=1S/C21H16F4N4O2S/c1-20(2)18(31)28(12-5-4-11(10-26)15(8-12)21(23

6 μM to 3

In glioblastoma cells

is a novel potent and selective inhibitor of proteasome Ubiquitin receptor RPN13/ADRM1

Vinblastine sulfate Size:Solid 2 mg CS-0087356Vinblastine is a natural alkaloid isolated from the plant Vinca rosea Linn. Vinblastine binds to tubulin and inhibits microtubule formation, resulting in disruption of mitotic spindle assembly and arrest of tumor cells in the M phase of the cell cycle. This agent may also interfere with amino acid, cyclic AMP, and glutathione metabolism; calmodulin dependent Ca++ transport ATPase activity; cellular respiration; and nucleic acid and lipid biosynthesis.

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