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VTP-27999 demonstrated excellent selectivity over related and unrelated off-targets
16-dimethyl-13-oxa-9λ⁶-thia-1
Smiles: COC1C=C(C=CC=1O)[C@H]1OC[C@@H]2[C@H](OC[C@@H]21)C1C=C(OC)C(=CC=1)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
ClH/c1-15-12-5-3-2-4-10(12)11-6-8-14-9-7-13(11)15
Smiles: C#CCOCCOCCOCCOCCOCCOCCOCCOCCOCCBr
N-(Azido-PEG2)-N-Boc-PEG4-NHS ester isolone farnesylate VTP-27999 demonstrated excellent selectivity overN (Azido PEG2) N Boc PEG4 NHS ester is a PEG based PROTAC linker that can be used in the synthesis of PROTACs. Product information CAS Number: 2093153 95 6 Molecular Weight: 619. 66 Formula: C26H45N5O12 Chemical Name: 2,5 dioxopyrrolidin 1 yl 1 (13 azido 2,2 dimethyl 4 oxo 3,8,11 trioxa 5 azatridecan 5 yl) 3,6,9,12 tetraoxapentadecan 15 oate Smiles: CC(C)(C)OC(=O)N(CCOCCOCCN=[N+]=[N ])CCOCCOCCOCCOCCC(=O)ON1C(=O)CCC1=O InChiKey: JLYRAESBBJMWBK