Telotristat ethyl Size:10mg solid 9 mg/kg per day for

9 mg/kg per day for 14 days

1111/1440-1681

3 mg/kg) decreases MBP and increases HR

Chemical Name: 2-Chloro-4-[(1R

3S)-2-ethoxy-5-oxotetrahydrofuran-3-yl)pyrrolidine-2-carboxamide

Telotristat ethyl Size:10mg solid 9 mg/kg per day forTelotristat ethyl, also known as LX 1032 or LX 1606, is an oral serotonin synthesis inhibitor or peripheral tryptophan hydroxylase (TPH) inhibitor . Telotristat etiprate has activity in controlling diarrhea associated with carcinoid syndrome. LX1606 acts by inhibiting the enzyme tryptophan hydoxylase (TPH) and reduces serotonin production both inside and outside the GI tract without affecting brain serotonin levels. TPH is the rate limiting enzyme