An FGFR3/MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers
Targeting the facilitative glucose transporter GLUT1 inhibits the self-renewal and tumor-initiating capacity of cancer stem cells
[Epub ahead of print] PubMed PMID: 26079256
tight-binding inhibitor of Escherichia coli LpxC with Ki=4 nM
2 substrates of this enzyme
10074-G5 - CAS# 413611-93-5 60423 An FGFR3/MYC positive feedback loop10074 G5, CAS No. 413611 93 5, is a c Myc Max interaction inhibitor. 10074 G5, similarly to 10058 F4 (#F3680), specifically inhibits this interaction by binding to c Myc, thus preventing C Myc specific DNA binding and target genes regulation. Product information CAS Number: 413611 93 5 Molecular Weight: 332. 31 Formula: C18H12N4O3 Synonym: 10074 G5 10074G5 4 nitro N (2 phenylphenyl) 2,1,3 benzoxadiazol 7 amine N 2 Biphenylyl 7 nitro 2,1,3